The Covid-19 pandemic to a greater extent than the earlier epidemics of the first two decades of the 21st century directed public attention to the distinctness of infectious diseases caused by viruses, their specificity and agency. The authors of the volume Myśląc z wirusami (Thinking with Viruses) are interested in scientific, cultural and artistic discourses on epidemics with their typical representations and materializations of viruses (also computer viruses and other manifestations of virality in social life). This thematic focus is reflected in the division of the volume into two parts. The first one, Inne epidemie (Other Epidemics) features articles that situate a variety of—contemporary and historical—representations of epidemics against a broad background of ecological relations and environmental catastrophes. The articles are particularly focused on demonstrating the consequences of employing virus as a metaphor to capture the spreading of various, not necessarily biotic pathogens endangering the health of humans and non-humans within complex ecologies. The texts gathered in the second part, titled Inne wirusy (Other Viruses) argue that thinking with viruses helps to search for ways out of today’s civilizational impasse, by destabilizing arrangements of power, scientific categorizations practiced today and social divisions. For this reason the articles in this part in various contexts refer to the figure of Virus, which Elizabeth A. Povinelli in her Geontologies defines as “a figure for that which seeks to disrupt the current arrangements of Life and Nonlife”. The transdisciplinary approach to thinking with viruses offered in the volume encourages to not only question the accepted borders between living and non-living entities, but also to represent the relations between them in scientific, cultural and artistic discourses in hitherto unknown ways. In ways which make it possible to imagine such alliances and coalitions within more-than-human, natural-cultural-technological networks of exchange and influence that offer a chance for survival.